The gene mutations and subtelomeric DNA methylation in immunodeficiency, centromeric instability and facial anomalies syndrome

Immunodeficiency, centromeric instability and facial anomalies syndrome (ICF) is a rare autosomal recessive disorder, which is characteristic of a severe impairment of immunity. In the genetic aspect, ICF is featured with mutations primarily located in the specific genes (DNMT3B for ICF1, ZBTB24 for...

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Bibliographic Details

Published in:	Autoimmunity
Main Authors:	Haochang Hu, Chujia Chen, Shanping Shi, Bin Li, Shiwei Duan
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2019-08-01
Subjects:	gene mutation subtelomere epigenetic alteration telomere length immunodeficiency centromeric instability and facial anomalies syndrome
Online Access:	http://dx.doi.org/10.1080/08916934.2019.1657846