Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression

Eya proteins are characterised by phosphatase activity associated with both the evolutionary conserved region and the less conserved N-terminal domain (NTD). Here the authors show that NTD mediates the interaction with PP2A and regulates c-Myc phosphorylation and stability, potentially switching PP2...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Lingdi Zhang, Hengbo Zhou, Xueni Li, Rebecca L Vartuli, Michael Rowse, Yongna Xing, Pratyaydipta Rudra, Debashis Ghosh, Rui Zhao, Heide L Ford
Format:	Article
Language:	English
Published:	Nature Portfolio 2018-03-01
Online Access:	https://doi.org/10.1038/s41467-018-03327-4