Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform

Abstract Regulated cell death plays a central role in tissue homeostasis, disease progression, and therapeutic responses. However, tools to study these processes with high spatiotemporal resolution in physiologically relevant systems remain limited. Here, we present a fluorescent reporter cell syste...

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Bibliographic Details
Published in:Cell Death Discovery
Main Authors: Selen Selcen, Lena Wieland, Tiago De Oliveira, Michael Ghadimi, Lena-Christin Conradi, Günter Schneider, Leonie Witte, Matthias Wirth
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Online Access:https://doi.org/10.1038/s41420-025-02662-y