Exacerbation of celecoxib-induced renal injury by concomitant administration of misoprostol in rats.

Nonsteroidal anti-inflammatory drugs (NSAIDs) can produce adverse effects by inhibiting prostaglandin (PG) synthesis. A PGE1 analogue, misoprostol, is often utilized to alleviate NSAID-related gastrointestinal side effects. This study examined the effect of misoprostol on celecoxib renal toxicity. A...

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書誌詳細

出版年:	PLoS ONE
主要な著者:	Dustin L Cooper, Derek E Murrell, Christopher M Conder, Victoria E Palau, Grace E Campbell, Shaun P Lynch, James W Denham, Angela V Hanley, Kenny W Bullins, Peter C Panus, Krishna Singh, Sam Harirforoosh
フォーマット:	論文
言語:	英語
出版事項:	Public Library of Science (PLoS) 2014-01-01
オンライン･アクセス:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089087&type=printable