Nintedanib Reduces Muscle Fibrosis and Improves Muscle Function of the Alpha-Sarcoglycan-Deficient Mice

Sarcoglycanopathies are a group of recessive limb-girdle muscular dystrophies, characterized by progressive muscle weakness. Sarcoglycan deficiency produces instability of the sarcolemma during muscle contraction, leading to continuous muscle fiber injury eventually producing fiber loss and replacem...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Jorge Alonso-Pérez, Ana Carrasco-Rozas, Maria Borrell-Pages, Esther Fernández-Simón, Patricia Piñol-Jurado, Lina Badimon, Lutz Wollin, Cinta Lleixà, Eduard Gallardo, Montse Olivé, Jordi Díaz-Manera, Xavier Suárez-Calvet
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	sarcoglycanopathy Sgca muscular dystrophy fibrosis nintedanib mice
Online Access:	https://www.mdpi.com/2227-9059/10/10/2629