Comparison of norepinephrine with a combined non-catecholaminergic therapy in a porcine model of refractory cardiac arrest resuscitated with VA-ECMO

Abstract Introduction Post-cardiac arrest syndrome (PCAS) under veno-arterial ECMO (VA-ECMO) is frequently complicated by severe vasoplegia and microcirculation failure. Conventional resuscitation relies heavily on catecholamines and crystalloids loading, which may exacerbate endothelial dysfunction...

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Bibliographic Details

Published in:	Intensive Care Medicine Experimental
Main Authors:	Thomas Klein, Vincent Elsensohn, Mathilde Martin-Schouler, Daniel Grandmougin, Thomas Raze, N.’Guyen Tran, Bruno Levy
Format:	Article
Language:	English
Published:	SpringerOpen 2026-04-01
Subjects:	Cardiac arrest Veno-arterial extracorporeal membrane oxygenation Vasoplegia
Online Access:	https://doi.org/10.1186/s40635-026-00895-4