Heterogeneity in proline hydroxylation of fibrillar collagens observed by mass spectrometry.

Collagen is the major protein in the extracellular matrix and plays vital roles in tissue development and function. Collagen is also one of the most processed proteins in its biosynthesis. The most prominent post-translational modification (PTM) of collagen is the hydroxylation of Pro residues in th...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Michele Kirchner, Haiteng Deng, Yujia Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Online Access:https://doi.org/10.1371/journal.pone.0250544