Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis

Severe coronavirus disease (COVID-19) is accompanied by acute respiratory distress syndrome and pulmonary pathology, and is presented mostly with an inflammatory cytokine release, a dysregulated immune response, a skewed neutrophil/lymphocyte ratio, and a hypercoagulable state. Though vaccinations h...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Zaigham Abbas Rizvi, Prabhakar Babele, Srikanth Sadhu, Upasna Madan, Manas Ranjan Tripathy, Sandeep Goswami, Shailendra Mani, Sachin Kumar, Amit Awasthi, Madhu Dikshit
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Subjects:	Glycyrrhiza glabra SARS-CoV-2 hamster model mice and human neutrophil functions Th2/Th17 differentiation NETosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.945583/full