Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukemia

Retrotransposons such as LINE-1 and Alu comprise >25% of the human genome. While global hypomethylation of these elements has been widely reported in solid tumours, their epigenetic dysregulation is yet to be characterised in chronic lymphocytic leukaemia, and there has been scant consideration...

Full description

Bibliographic Details

Published in:	Haematologica
Main Authors:	Timothy M. Barrow, Nicole Wong Doo, Roger L. Milne, Graham G. Giles, Elaine Willmore, Gordon Strathdee, Hyang-Min Byun
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2020-01-01
Online Access:	https://haematologica.org/article/view/9594