Integrating multi-cohort machine learning and clinical sample validation to explore peripheral blood mRNA diagnostic biomarkers for prostate cancer

Abstract Background The global incidence of prostate cancer (PCa) has been rising annually, and early diagnosis and treatment remain pivotal for improving therapeutic outcomes and patient prognosis. Concurrently, advancements in liquid biopsy technology have facilitated disease diagnosis and monitor...

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Bibliographic Details

Published in:	Cancer Cell International
Main Authors:	Xingyu Zhong, Yuxuan Yang, Haodong He, Yifan Xiong, Mingliang Zhong, Shaogang Wang, Qidong Xia
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Prostate cancer Liquid biopsy Cell-free RNA Biomarker Precision diagnostic
Online Access:	https://doi.org/10.1186/s12935-025-03788-w