The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis

Cytokinesis requires activation of the GTPase RhoA. ECT-2, the exchange factor responsible for RhoA activation, is regulated to ensure spatiotemporal control of contractile ring assembly. Centralspindlin, composed of the Rho family GTPase-activating protein (RhoGAP) MgcRacGAP/CYK-4 and the kinesin M...

書誌詳細
出版年:	eLife
主要な著者:	Donglei Zhang, Michael Glotzer
フォーマット:	論文
言語:	英語
出版事項:	eLife Sciences Publications Ltd 2015-08-01
主題:	cytokinesis Rho GTPase RhoGAP RhoGEF centralspindlin Rac
オンライン･アクセス:	https://elifesciences.org/articles/08898

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