Phenotype microarrays reveal metabolic dysregulations of neurospheres derived from embryonic Ts1Cje mouse model of Down syndrome.

Down syndrome (DS), is the most common cause of intellectual disability, and is characterized by defective neurogenesis during perinatal development. To identify metabolic aberrations in early neurogenesis, we profiled neurospheres derived from the embryonic brain of Ts1Cje, a mouse model of Down sy...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Eryse Amira Seth, Han-Chung Lee, Hadri Hadi Bin Md Yusof, Norshariza Nordin, Yoke Kqueen Cheah, Eric Tatt Wei Ho, King-Hwa Ling, Pike-See Cheah
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2020-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0236826