Liver specification of human iPSC-derived endothelial cells transplanted into mouse liver

Background & Aims: Liver sinusoidal endothelial cells (LSECs) are important in liver development, regeneration, and pathophysiology, but the differentiation process underlying their tissue-specific phenotype is poorly understood and difficult to study because primary human cells are scarce....

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Bibliographic Details

Published in:	JHEP Reports
Main Authors:	Kiryu K. Yap, Jan Schröder, Yi-Wen Gerrand, Aleksandar Dobric, Anne M. Kong, Adrian M. Fox, Brett Knowles, Simon W. Banting, Andrew G. Elefanty, Eduoard G. Stanley, George C. Yeoh, Glen P. Lockwood, Victoria C. Cogger, Wayne A. Morrison, Jose M. Polo, Geraldine M. Mitchell
Format:	Article
Language:	English
Published:	Elsevier 2024-05-01
Subjects:	Liver Liver sinusoidal endothelial cells Tissue specification Induced pluripotent stem cells Cell transplantation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589555924000247