Anti-Scg3 Gene Therapy to Treat Choroidal Neovascularization in Mice

Neovascular age-related macular degeneration (nAMD) with choroidal neovascularization (CNV) is a leading cause of blindness in the elderly in developed countries. The disease is currently treated with anti-angiogenic biologics, including aflibercept, against vascular endothelial growth factor (VEGF)...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Chengchi Huang, Liyang Ji, Avinash Kaur, Hong Tian, Prabuddha Waduge, Keith A. Webster, Wei Li
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Subjects:	age-related macular degeneration choroidal neovascularization gene therapy secretogranin III (Scg3) anti-Scg3 gene therapy disease-targeted gene therapy
Online Access:	https://www.mdpi.com/2227-9059/11/7/1910