Differential regulation by CD47 and thrombospondin-1 of extramedullary erythropoiesis in mouse spleen

Extramedullary erythropoiesis is not expected in healthy adult mice, but erythropoietic gene expression was elevated in lineage-depleted spleen cells from Cd47−/− mice. Expression of several genes associated with early stages of erythropoiesis was elevated in mice lacking CD47 or its signaling ligan...

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Bibliographic Details

Published in:	eLife
Main Authors:	Rajdeep Banerjee, Thomas J Meyer, Margaret C Cam, Sukhbir Kaur, David D Roberts
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2024-07-01
Subjects:	extramedullary erythropoiesis spleen RNA sequencing erythroid progenitors CD47 thrombospondin-1
Online Access:	https://elifesciences.org/articles/92679