The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

<b>Background:</b> Ischemia/reperfusion (I/R) caused by ischemic stroke treatments leads to brain injury, and autophagy plays a role in the pathology. Astragaloside IV is a potential neuroprotectant, but its underlying mechanism on cerebral I/R injury needs to be explored. The objective...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Yi Zhang, Ying Zhang, Xiao-fei Jin, Xiao-hong Zhou, Xian-hui Dong, Wen-tao Yu, Wei-juan Gao
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Subjects:	Astragaloside IV cerebral ischemia/reperfusion injury autophagy apoptosis mechanism
Online Access:	https://www.mdpi.com/1420-3049/24/9/1838