BLINK enables ultrafast tandem mass spectrometry cosine similarity scoring

Abstract Metabolomics has a long history of using cosine similarity to match experimental tandem mass spectra to databases for compound identification. Here we introduce the Blur-and-Link (BLINK) approach for scoring cosine similarity. By bypassing fragment alignment and simultaneously scoring all p...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Thomas V. Harwood, Daniel G. C. Treen, Mingxun Wang, Wibe de Jong, Trent R. Northen, Benjamin P. Bowen
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-08-01
Online Access:	https://doi.org/10.1038/s41598-023-40496-9