Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics

The 60 kDa heat shock protein (Hsp60) is classically known as a mitochondrial chaperonin protein working together with co-chaperonin 10 kDa heat shock protein (Hsp10). This chaperonin complex is essential for folding proteins newly imported into mitochondria. However, Hsp60, and/or Hsp10 have also b...

Full description

Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Qianli Meng, Bingbing X. Li, Xiangshu Xiao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-04-01
Subjects:	autoimmune cancer chaperone GroEL GroES Hsp60
Online Access:	http://journal.frontiersin.org/article/10.3389/fmolb.2018.00035/full