Protocol to establish a stable MLL-AF9_AML mouse model

Summary: Acute myeloid leukemia (AML) is one of the most common and fatal forms of hematopoietic malignancies. Here, we describe a mouse MLL-AF9_AML model to investigate AML. We have optimized the protocols for retrovirus infection, bone marrow transplantation (BMT), and leukemia monitoring to creat...

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Bibliographic Details
Published in:STAR Protocols
Main Authors: Jun Lu, Huanhuan Zhao, Lingling Yang, Xi Jiang
Format: Article
Language:English
Published: Elsevier 2022-09-01
Subjects:
Cancer
Cell isolation
Cell separation/fractionation
Cell-based Assays
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722004397

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http://www.sciencedirect.com/science/article/pii/S2666166722004397

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