Fixed combination of palmitoylethanolamide and melatonin in preventive therapy of migraine: results from a randomized clinical trial

IntroductionMigraines are neurological disorders which significantly impact quality of life. Current pharmacological treatments often have adverse effects, prompting the search for alternatives with fewer side effects. Several studies have described the antimigraine properties of palmitoylethanolami...

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Bibliographic Details

Published in:	Frontiers in Nutrition
Main Authors:	Vincenzo Piccolo, Adua Marzocchi, Maria Maisto, Vincenzo Summa, Gian Carlo Tenore, Angela Amoresano
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	migraine palmitoylethanolamide melatonin supplement clinical trial
Online Access:	https://www.frontiersin.org/articles/10.3389/fnut.2025.1560654/full