Development and Evaluation of a Modified Fixed-Dose Combination Antihypertensive Tablet Containing S-Amlodipine Besylate: A Bioequivalence and Stability Study

<b>Background</b>/<b>Objectives</b>: Fixed-dose combination (FDC) antihypertensive medications containing olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide are widely used for the treatment of essential hypertension. Although effective, the use of racemic aml...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Hyeon Woo Moon, Jin-Hyuk Jeong, Chun-Woong Park
Format:	Article
Language:	English
Published:	MDPI AG 2025-09-01
Subjects:	S-amlodipine besylate olmesartan medoxomil hydrochlorothiazide fixed-dose combination bilayer tablet stability
Online Access:	https://www.mdpi.com/1999-4923/17/9/1235