Signaling Through gp130 Compromises Suppressive Function in Human FOXP3+ Regulatory T Cells

The CD4+FOXP3+ regulatory T cell (Treg) subset is an indispensable mediator of immune tolerance. While high and stable expression of the transcription factor FOXP3 is considered a hallmark feature of Treg cells, our previous studies have demonstrated that the human FOXP3+ subset is functionally hete...

詳細記述

書誌詳細
出版年:Frontiers in Immunology
主要な著者: Khalid Bin Dhuban, Sabrina Bartolucci, Eva d'Hennezel, Ciriaco A. Piccirillo
フォーマット: 論文
言語:英語
出版事項: Frontiers Media S.A. 2019-07-01
主題:
オンライン・アクセス:https://www.frontiersin.org/article/10.3389/fimmu.2019.01532/full