EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases*

Enteropathogenic E. coli (EPEC) is a Gram-negative bacterial pathogen that causes persistent diarrhea. Upon attachment to the apical plasma membrane of the intestinal epithelium, the pathogen translocates virulence proteins called effectors into the infected cells. These effectors hijack numerous ho...

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Bibliographic Details

Published in:	Gut Microbes
Main Authors:	Ipsita Nandi, Rachana Pattani Ramachandran, Deborah E. Shalev, Dina Schneidman-Duhovny, Raisa Shtuhin-Rahav, Naomi Melamed-Book, Efrat Zlotkin-Rivkin, Alexander Rouvinski, Ilan Rosenshine, Benjamin Aroeti
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Subjects:	Enteropathogenic e. coli type III secreted effectors EspH Rab GTPases Rho GTPases phosphoinositides (PIs)
Online Access:	https://www.tandfonline.com/doi/10.1080/19490976.2024.2400575