A statistical framework for detecting therapy-induced resistance from drug screens
Abstract Resistance to therapy remains a significant challenge in cancer treatment, often due to the presence of a stem-like cell population that drives tumor recurrence post-treatment. Moreover, many anticancer therapies induce plasticity, converting initially drug-sensitive cells to a more resista...
| Published in: | npj Systems Biology and Applications |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Online Access: | https://doi.org/10.1038/s41540-025-00560-8 |