A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma

A sensitive and reproducible liquid chromatography-tandem mass spectrometry (LC-MS/MS) system was developed and fully validated for the simultaneous determination of ephedrine and pseudoephedrine in human plasma after oral administration of the herbal prescription Ojeok-san (OJS); 2-phenylethylamine...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Sooyoung Lee, Wang-Seob Shim, Heejo Yoo, Sanghee Choi, Jiyoung Yoon, Kwang-Young Lee, Eun-Kyoung Chung, Byung-Cheol Lee, Sung-Vin Yim, Bo-Hyung Kim, Kyung-Tae Lee
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Subjects:	ephedrine pseudoephedrine liquid chromatography-tandem mass spectrometry bioanalytical method validation pharmacokinetics healthy volunteers
Online Access:	https://www.mdpi.com/1420-3049/26/22/6991