Polyunsaturated fatty acids and their endocannabinoid-related metabolites activity at human TRPV1 and TRPA1 ion channels expressed in HEK-293 cells

Background Polyunsaturated fatty acids (PUFAs), particularly Omega-3 (ω-3) and Omega-6 (ω-6) PUFAs, may exert neuroprotective effects via the endocannabinoid system (ECS) and are promoted as brain health supplements. However, despite their potential role in endocannabinoid biosynthesis, the impact o...

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Bibliographic Details

Published in:	PeerJ
Main Authors:	Atnaf Abate, Marina Santiago, Alfonso Garcia-Bennett, Mark Connor
Format:	Article
Language:	English
Published:	PeerJ Inc. 2025-03-01
Subjects:	Cannabinoid Fatty acid Inflammation Omega-3 TRP channel
Online Access:	https://peerj.com/articles/19125.pdf