Interconvertible Hydrochlorothiazide–Caffeine Multicomponent Pharmaceutical Materials: A Solvent Issue

The design of new multicomponent pharmaceutical materials that involve different active pharmaceutical ingredients (APIs), e.g., drug-drug cocrystals, is a novel and interesting approach to address new therapeutic challenges. In this work, the hydrochlorothiazide-caffeine (HCT–CAF) codrug and its me...

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Bibliographic Details
Published in:Crystals
Main Authors: Cristóbal Verdugo-Escamilla, Carolina Alarcón-Payer, Antonio Frontera, Francisco Javier Acebedo-Martínez, Alicia Domínguez-Martín, Jaime Gómez-Morales, Duane Choquesillo-Lazarte
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Subjects:
cocrystal
codrug
hydrochlorothiazide
caffeine
mechanochemical synthesis
Online Access:https://www.mdpi.com/2073-4352/10/12/1088

Internet

https://www.mdpi.com/2073-4352/10/12/1088

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