Nanotechnology for microglial targeting and inhibition of neuroinflammation underlying Alzheimer’s pathology

Abstract Background Alzheimer's disease (AD) is considered to have a multifactorial etiology. The hallmark of AD is progressive neurodegeneration, which is characterized by the deepening loss of memory and a high mortality rate in the elderly. The neurodegeneration in AD is believed to be exace...

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Bibliographic Details

Published in:	Translational Neurodegeneration
Main Authors:	Hoda M. Gebril, Aravind Aryasomayajula, Mariana Reis Nogueira de Lima, Kathryn E. Uhrich, Prabhas V. Moghe
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Subjects:	Amphiphilic nanoparticle Microglia Fibril amyloid beta Alzheimer’s disease Neuroinflammation Scavenger receptor
Online Access:	https://doi.org/10.1186/s40035-023-00393-7