Impact of intra-articular high-concentration hyaluronic acid administration on the innate immune response in experimental knee osteoarthritis

Abstract Background Osteoarthritis (OA) is characterized by a loss of the joint viscoelastic properties. Hyaluronic acid (HA) intraarticular injections restore viscoelasticity, alleviating pain and improving patient function. Larger amounts of HA in a single injection could lead to greater efficacy,...

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發表在:	BMC Musculoskeletal Disorders
Main Authors:	Gabriel Herrero-Beaumont, Miguel Marco-Bonilla, Alberto Migliore, Alberto López-Reyes, Alberto Irigaray-Moreno, Aránzazu Mediero, Raquel Largo
格式:	Article
語言:	英语
出版:	BMC 2025-08-01
主題:	Osteoarthritis Hyaluronic acid Cartilage damage, synovitis Innate immune response
在線閱讀:	https://doi.org/10.1186/s12891-025-09061-5