In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint

Biodegradable and bioresponsive polymer-based nanoparticles (NPs) can be used for oligonucleotide delivery, making them a promising candidate for mRNA-based therapeutics. In this study, we evaluated and optimized the efficiency of a cationic, hyperbranched poly(amidoamine)s-based nanoparticle system...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Biomedicines
المؤلفون الرئيسيون:	Lisa Sturm, Bettina Schwemberger, Ursula Menzel, Sonja Häckel, Christoph E. Albers, Christian Plank, Jaap Rip, Mauro Alini, Andreas Traweger, Sibylle Grad, Valentina Basoli
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2021-07-01
الموضوعات:	transfection bioresponsive polymer-based nanoparticles joint therapies therapeutic mRNA biologicals
الوصول للمادة أونلاين:	https://www.mdpi.com/2227-9059/9/7/794