Pharmacokinetics and pharmacodynamics of intranasal and intramuscular administration of naloxone in working dogs administered fentanyl

Abstract Background Working dogs exposed to narcotics might require reversal in the field. Objective To explore the pharmacokinetic and pharmacodynamic effects of naloxone administered intramuscularly (IM) or intranasally (IN) to reverse fentanyl sedation in working dogs. Animals Ten healthy, workin...

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Bibliographic Details

Published in:	Journal of Veterinary Internal Medicine
Main Authors:	Ciara A. Barr, Joanne Haughan, Giacomo Gianotti, Kelley Varner, Kenneth J. Drobatz, Darko Stefanovski, Mary Robinson, Mark Pennington, Amanda McGuire, Cynthia M. Otto
Format:	Article
Language:	English
Published:	Wiley 2023-11-01
Subjects:	opioid overdose reversal sedation
Online Access:	https://doi.org/10.1111/jvim.16901