In Vitro Cytotoxicity of Oleanolic/Ursolic Acids-Loaded in PLGA Nanoparticles in Different Cell Lines

Oleanolic (OA) and ursolic (UA) acids are recognized triterpenoids with anti-cancer properties, showing cell-specific activity that can be enhanced when loaded into polymeric nanoparticles. The cytotoxic activity of OA and UA was assessed by Alamar Blue assay in three different cell lines, i.e., Hep...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Amélia M. Silva, Helen L. Alvarado, Guadalupe Abrego, Carlos Martins-Gomes, Maria L. Garduño-Ramirez, María L. García, Ana C. Calpena, Eliana B. Souto
Format:	Article
Language:	English
Published:	MDPI AG 2019-07-01
Subjects:	oleanolic acid ursolic acid cytotoxicity PLGA polymeric nanoparticles retinoblastoma cell line
Online Access:	https://www.mdpi.com/1999-4923/11/8/362