Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1 as Potential Drugs for Type 2 Diabetes Mellitus—A Systematic Review of Clinical and In Vivo Preclinical Studies

Diabetes mellitus is a pathology with increasing frequency in society, being one of the main causes of death worldwide. For this reason, new therapeutic targets have been studied over the years. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an enzyme responsible for reducing cortisone to its...

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Bibliographic Details
Published in:Scientia Pharmaceutica
Main Authors: Cristiana Almeida, Cristina Monteiro, Samuel Silvestre
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Subjects:
Online Access:https://www.mdpi.com/2218-0532/89/1/5