Sivelestat for septic patients with acute respiratory distress syndrome: a systematic review and meta-analysis of a deadly duo

BackgroundAcute respiratory distress syndrome (ARDS) is one of the most common organ dysfunctions in sepsis. The potential benefits of sivelestat, a selective inhibitor of neutrophil elastase, for patients with septic ARDS remain unclear. The current systematic review and meta-analysis aimed to eval...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Wen-He Zheng, Yan-Ge Hu, Da-Xing Yu, Hui-Bin Huang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	sivelestat neutrophil elastase inhibitors acute respiratory distress syndrome mortality meta-analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1679717/full