Investigating the molecular mechanisms and clinical potential of APO+ endothelial cells associated with PANoptosis in the tumor microenvironment of hepatocellular carcinoma using single-cell sequencing data

Introduction: PANoptosis is a newly identified form of programmed cell death that integrates elements of pyroptosis, apoptosis, and necroptosis. It plays a pivotal role in shaping the tumor immune microenvironment. Despite its significance, the specific functions and mechanisms of PANoptosis within...

Full description

Bibliographic Details

Published in:	Translational Oncology
Main Authors:	Zhaorui Cheng, Xiangyu Yang, Yi Ren, Huimin Wang, Qi Zhang, Sailing Lin, Wenhao Wu, Xiaolu Yang, Jiahan Zheng, Xinzhu Liu, Xin Tao, Xiaoyong Chen, Yuxin Qian, Xiushen Li
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Subjects:	Hepatocellular carcinoma PANoptosis Tumor microenvironment (TME) Endothelial cells Immunotherapy
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523325001330