Yeast Surface Display Platform for Rapid Selection of an Antibody Library via Sequential Counter Antigen Flow Cytometry

Yeast surface display techniques have been increasingly employed as a tool for both the discovery and affinity maturation of antibodies. In this study, we describe the use of yeast surface display for the selection and affinity maturation of antibodies targeted to small molecules (haptens). In this...

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Bibliographic Details

Published in:	Antibodies
Main Authors:	Bhupal Ban, Robert C. Blake, Diane A. Blake
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Subjects:	antibody-based biosensors yeast surface display single chain variable fragments (scFv) hexavalent uranium (UO<sub>2</sub><sup>2+</sup>) affinity maturation error prone PCR
Online Access:	https://www.mdpi.com/2073-4468/11/4/61