An Efficient Three Component One-Pot Synthesis of 5-Amino-7-aryl-7,8-dihydro-[1,2,4] triazolo[4,3-a]-pyrimidine-6-carbonitriles

A series of novel 5-amino-7-aryl-7,8-dihydro-[1,2,4] triazolo[4,3-a]-pyrimidine-6-carbonitriles were synthesized by a one-pot reaction of 3-amino-1,2,4-triazole, malononitrile and aryl aldehydes in the presence of 20 mol% NaOH in ethanol under heating or ultrasonic irradiation. The structures of the...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Sun Wan-Fu, Wetengul Kamil, Anagu Tuoheti, Keyume Ablajan
Format:	Article
Language:	English
Published:	MDPI AG 2012-02-01
Subjects:	1,2,4-triazolo[4,3-a]pyrimidine three component reactions one-pot synthesis ultrasound irradiation
Online Access:	http://www.mdpi.com/1420-3049/17/2/1860/