The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy

Breakthroughs in anti-tumor immunity have led to unprecedented advances in immunotherapy, yet it is now clear that the tumor microenvironment (TME) restrains immunity. T cells must substantially increase nutrient uptake to mount a proper immune response and failure to obtain sufficient nutrients or...

書誌詳細
出版年:	eLife
主要な著者:	Aaron R Lim, W Kimryn Rathmell, Jeffrey C Rathmell
フォーマット:	論文
言語:	英語
出版事項:	eLife Sciences Publications Ltd 2020-05-01
主題:	immunometabolism tumor microenvironment tumor-infiltrating lymphocytes t cells immunotherapy cancer
オンライン･アクセス:	https://elifesciences.org/articles/55185

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