Subthreshold Cannabidiol Potentiates Levetiracetam in the Kainic Acid Model of Temporal Lobe Epilepsy: A Pilot Study

Refractoriness to antiseizure medications is still a major concern in the pharmacotherapy of epilepsy. For this reason, we decided to evaluate the combination of levetiracetam and cannabidiol, administered at a subthreshold dose, to limit the possible adverse effects of this phytocannabinoid. We adm...

Full description

Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Chiara Lucchi, Mattia Marcucci, Kawther Ameen Muhammed Saeed Aledresi, Anna-Maria Costa, Giuseppe Cannazza, Giuseppe Biagini
Format:	Article
Language:	English
Published:	MDPI AG 2024-09-01
Subjects:	cannabidiol epilepsy kainic acid levetiracetam
Online Access:	https://www.mdpi.com/1424-8247/17/9/1187