Orchestration of human multi‐lineage hematopoietic cell development by humanized in vivo bone marrow models

Abstract Hematopoiesis develops in the bone marrow (BM) where multiple interactions regulate the differentiation and preservation of hematopoietic stem and progenitor cells (HSPCs). Immune‐deficient murine models have enabled the analysis of molecular and cellular regulation of human HSPCs, but the...

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Bibliographic Details
Published in:HemaSphere
Main Authors: Laurent Renou, Wenjie Sun, Chloe Friedrich, Klaudia Galant, Cecile Conrad, Anne Consalus, Evelia Plantier, Katharina Schallmoser, Linda Krisch, Vilma Barroca, Saryami Devanand, Nathalie Dechamps, Andreas Reinisch, Jelena Martinovic, Alessandra Magnani, Lionel Faivre, Daniel Lewandowski, Julien Calvo, Leila Perie, Olivier Kosmider, Françoise Pflumio
Format: Article
Language:English
Published: Wiley 2025-04-01
Online Access:https://doi.org/10.1002/hem3.70120