Flavivirus Capsid Proteins Inhibit the Interferon Response

Zika virus (ZIKV) establishes persistent infections in multiple human tissues, a phenomenon that likely plays a role in its ability to cause congenital birth defects and neurological disease. Multiple nonstructural proteins encoded by ZIKV, in particular NS5, are known to suppress the interferon (IF...

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Bibliographic Details
Published in:Viruses
Main Authors: Adriana M. Airo, Alberto Felix-Lopez, Valeria Mancinelli, Danyel Evseev, Joaquin Lopez-Orozco, Kathy Shire, Patrick Paszkowski, Lori Frappier, Katharine E. Magor, Tom C. Hobman
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Subjects:
flaviviruses
global transcription
capsid protein
interferon response
TRIM25
Zika virus
Online Access:https://www.mdpi.com/1999-4915/14/5/968

Internet

https://www.mdpi.com/1999-4915/14/5/968

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