Intestinal endothelial cells increase HIV infection and latency in resting and activated CD4 + T cells, particularly affecting CCR6 + CD4 + T cells

Abstract Background With suppressive antiretroviral therapy, HIV infection is well-managed in most patients. However, eradication and cure are still beyond reach due to latent viral reservoirs in CD4 + T cells, particularly in lymphoid tissue environments including the gut associated lymphatic tissu...

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Bibliographic Details

Published in:	Retrovirology
Main Authors:	Jessica Eddy, Fisher Pham, Rachel Chee, Esther Park, Nathan Dapprich, Stacy L. DeRuiter, Anding Shen
Format:	Article
Language:	English
Published:	BMC 2023-05-01
Subjects:	HIV Resting CD4 + T Latent reservoir Endothelial cells Viral reservoir CCR6 + Th17 cell
Online Access:	https://doi.org/10.1186/s12977-023-00621-y