Stress-induced ribosome degradation in Bacillus subtilis is mediated by the RNase Y-specificity complex

Abstract Limiting ribosome synthesis and activity is crucial for adaptation to stresses, such as heat or nutrient starvation. In Bacillus subtilis, this can be achieved through the coordinated action of the alarmones (p)ppGpp and the transcription factor Spx. Here, we performed a genetic screen to i...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Fabián A. Cornejo, Kristina Driller, Rina Ahmed-Begrich, Katja Schmidt, Michael Jahn, Vivekanandan Shanmuganathan, Karin Hahnke, Florian Kondrot, Thomas F. Wulff, Sebastian Rämisch, Kathirvel Alagesan, Emmanuelle Charpentier, Kürşad Turgay
Format:	Article
Language:	English
Published:	Nature Portfolio 2026-06-01
Online Access:	https://doi.org/10.1038/s41467-026-73310-x