Pan-cancer association of a centrosome amplification gene expression signature with genomic alterations and clinical outcome.
Centrosome amplification (CA) is a common feature of human tumours and a promising target for cancer therapy. However, CA's pan-cancer prevalence, molecular role in tumourigenesis and therapeutic value in the clinical setting are still largely unexplored. Here, we used a transcriptomic signatur...
| الحاوية / القاعدة: | PLoS Computational Biology |
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| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Public Library of Science (PLoS)
2019-03-01
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| الوصول للمادة أونلاين: | https://doi.org/10.1371/journal.pcbi.1006832 |