A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.
An increasing number of genetic variants have been identified for many complex diseases. However, it is controversial whether risk prediction based on genomic profiles will be useful clinically. Appropriate statistical measures to evaluate the performance of genetic risk prediction models are requir...
| 發表在: | PLoS Genetics |
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| Main Authors: | , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Public Library of Science (PLoS)
2010-12-01
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| 在線閱讀: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151957/?tool=EBI |