A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.

An increasing number of genetic variants have been identified for many complex diseases. However, it is controversial whether risk prediction based on genomic profiles will be useful clinically. Appropriate statistical measures to evaluate the performance of genetic risk prediction models are requir...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	PLoS Genetics
المؤلفون الرئيسيون:	Hon-Cheong So, Pak C Sham
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Public Library of Science (PLoS) 2010-12-01
الوصول للمادة أونلاين:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151957/?tool=EBI

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