Immunotherapy of chimeric antigen receptor NK cells: status and its promising future

Chimeric antigen receptors (CARs) are genetically engineered fusion proteins composed of extracellular antigen-recognition domains and multiple intracellular signaling domains. Although CAR T-cell immunotherapy has achieved significant advancements in treating hematologic malignancies, its applicati...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Fang Wang, Zhaoyuan Huang, Xiaoming Feng, Mingxia Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	chimeric antigen receptors CAR NK cells natural killer cells immunotherapy NK
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608277/full