Prognosis and personalized medicine prediction by integrated whole exome and transcriptome sequencing of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a clinically and genetically heterogeneous disease. To better describe the clinical value of the main driver gene mutations of HCC, we analyzed the whole exome sequencing data of 125 patients, and combined with the mutation data in the public database, 14 main mutan...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Frontiers in Genetics
المؤلفون الرئيسيون:	Debao Li, Lei Lei, Jinsong Wang, Bo Tang, Jiuling Wang, Rui Dong, Wenjiong Shi, Guo Liu, Tingting Zhao, Yuzhang Wu, Yi Zhang
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2023-02-01
الموضوعات:	hepatocellular carcinoma whole exome sequencing RNA sequencing TP53 prognostic model
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1075347/full