Tet proteins: on track towards DNA demethylation?

Dynamic DNA methylation is a prerequisite for many developmental processes and maintenance of cellular integrity. In mammals however, mechanisms of active DNA demethylation have for long been elusive. The discovery of the ten-eleven translocation (Tet) family of enzymes that oxidize 5-methylcytosine...

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Bibliographic Details
Published in:Biomolecular Concepts
Main Author: Véron Nathalie
Format: Article
Language:English
Published: De Gruyter 2012-10-01
Subjects:
Online Access:https://doi.org/10.1515/bmc-2012-0022