Effect of galactosylceramide on stratum corneum intercellular lipid synthesis in a three-dimensional cultured human epidermis model

Intercellular lipids in the stratum corneum (SC), such as ceramide (CER), free fatty acid (FFA), and cholesterol (CHOL), contribute to the formation of stable lamellar structures in the SC, making them important for skin barrier function. β-Galactosylceramide (GalCer) is a glycosphingolipid that is...

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Bibliographic Details
Published in:Biochemistry and Biophysics Reports
Main Authors: Madoka Kage, Yurina Itaya, Jumpei Horikoshi, Yoshihiro Tokudome
Format: Article
Language:English
Published: Elsevier 2021-12-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821002296